Wolfberry Extract Powder

1.Product name: Wolfberry extract powder
2.Appearance: Reddish brown to brown powder
3.Purity: 10:1, 20:1, 30:1; Lycium barbarum polysaccharide 20 percent , 30 percent , 40 percent , 50 percent , 70 percent
4.Product Grade: Food grade
5.Botanical source.: Lycium barbarum
6.Extracted part: Fruit
7.Shelf life: 2 years
8.MOQ: 1KG

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Brief introduction of Wolfberry extract powder:

Lycium barbarum extract is extracted from the mature fruit of the dicotyledonous herb Solanaceae or Lycium barbarum ningxia. Modern analysis shows that the nutritious ingredients contained in wolfberry fruit are very rich. Each hectogram of wolfberry fruit contains 4.49 grams of crude protein, 2.33 grams of crude fat, 9.12 grams of carbohydrates, 96 mg of carotenoids, 0.053 mg of thiamine, and 0.053 mg of nuclear Flavin 0.137 mg, ascorbic acid 19.8 mg, betaine 0.26 mg, also rich in potassium, sodium, calcium, magnesium, iron, copper, manganese, zinc and other elements, as well as 22 kinds of amino acids and vitamins. The active ingredient is Lycium barbarum polysaccharide.

Wolfberry extract

Specification of Wolfberry extract powder:

Product Name	Wolfberry extract
Analysis Item	Specification	Result	Method
Appearance	Brown fine powder	Complies	Visual
Odor	Characteristic	Complies	Organoleptic
Sieve analysis	100 percent pass 80 mesh	Complies	80 mesh Screen
Loss on Drying	Less than or equal to 5.0 percent	3.40 percent	105 degree /3hrs
Residue on Ignition	Less than or equal to 5.0 percent	2.11 percent	750 degree /3hrs
Bulk Density	45-55g/100mL	50.2g/100mL	/
Extract Solvent	Ethanol Water	Complies	GC
Heavy Metals	<20ppm>	Complies	CP2010
As	<2ppm>	Complies	AAS
Residual Solvents	Eur.Pharm.5	Complies	GC
Total Plate Count	<1000cfu>	135cfu/g	CP2010
Yeast Mold	<100cfu>	35cfu/g	CP2010
E.Coli	Negative	Complies	CP2010
Salmonella	Negative	Complies	CP2010
Assay
Polysaccharides	Greater than or equal to 50 percent	Greater than or equal to 50.5 percent	HPLC

Function of Wolfberry extract powder:

1.Reproductive system protection

Wolfberry is used in traditional Chinese medicine to treat infertility. The protective mechanism of Lycium barbarum polysaccharide on rat reproductive system may be achieved through its antioxidant effect. Lycium barbarum polysaccharide can prolong the apoptosis time of heat-damaged mouse seminiferous epithelial cells in vitro, inhibit the expression of UV-induced lipid peroxidase and free radical-induced cytochrome C, and can also reduce the breakage of testis cells in mice Oxidation of DNA.

Lycium barbarum polysaccharide can significantly increase serum sex hormone levels and SOD activity in rats, and reduce MDA levels. Lycium barbarum polysaccharide can reduce the damage of spermatogenic cells caused by high temperature and H2O2, and promote the normal development of testicular germ cells. It is realized by the thalamus, pituitary, and gonadal axis, and has the function of repairing and protecting the chromosomes of spermatogenic cells after injury.

2.Antioxidant and Antiaging

The accumulation of oxidative stress will promote the aging process, and the anti-aging experiments of Lycium barbarum polysaccharide mostly use free radicals as toxin carriers. The antioxidant function of Lycium barbarum polysaccharide has been confirmed in a large number of in vitro experiments.

It has been reported that Lycium barbarum polysaccharide exhibits antioxidant capacity in various antioxidant systems in vitro, such as inhibiting the effect of 1,1-diphenyl-2-picrylhydrazine (DPPH) free radicals, significant reducing ability, superoxide Scavenging ability, inhibition of hydrogen peroxide free radical-mediated hemolysis of mouse erythrocytes and ferrous ion chelation ability.

Rat liver microsomal suspension or microsomal suspension with Lycium barbarum polysaccharide was irradiated with 60Co radiation. The results showed that Lycium barbarum polysaccharide could inhibit the loss of sulfhydryl protein caused by radiation, as well as superoxide dismutase (SOD), catalase ( CAT) and glutathione peroxidase inactivation, and there is a dose-response relationship, its effect is better than vitamin E.

The Lycium barbarum polysaccharide used in most reports is the total polysaccharide extract obtained from Lycium barbarum by degreasing, water extraction and alcohol precipitation. Luo Qiong reported in 200 that the in vitro antioxidant activity of Lycium barbarum water extract is higher than that of water extraction and alcohol precipitation. , and the latter is higher than the antioxidant capacity of the component Lycium barbarum polysaccharide X purified by DEAE cellulose column. Involved in antioxidant reactions.

Recently, Taiwanese scholars hydrolyzed the crude extract of Lycium barbarum polysaccharide by proteolysis and separated it with DEAE-Sepharose CL-6B column, and obtained 4 components including neutral polysaccharide (Lycium barbarum polysaccharide N) and 3 kinds of acidic polysaccharides. The antioxidant activity of water extract (CE) without alcohol precipitation, crude polysaccharide (CP), deproteinized polysaccharide (DP), deproteinized and dialyzed polysaccharide (DDP) prepared by alcohol precipitation was compared, and the results It shows that except CE and DDP, all of them can scavenge DPPH radical, 2,2-azo-bis-(3-ethane-6-sulfonic acid) (ABTS) radical, superoxide anion and hydroxyl radical. .

3.Immunomodulatory

Lycium barbarum polysaccharide affects immune regulation in various ways. The crude polysaccharide was further separated and purified by ion exchange chromatography to obtain a proteoglycan complex Lycium barbarum polysaccharide 3p, which has an immune stimulating effect. Lycium barbarum polysaccharide 3p can increase the expression of IL-2 and TNF in human peripheral blood mononuclear cells, and both mRNA and protein levels are dose-related with Lycium barbarum polysaccharide, indicating that it has enhanced immunity and potential anti-tumor effects.

Lycium barbarum polysaccharide 3p can inhibit the growth of transplanted S180 sarcoma, increase the phagocytic ability of macrophages, the proliferation of spleen macrophages and the antibody secretion of spleen cells, the viability of damaged T macrophages, the expression of IL2 mRNA and reduce lipid Peroxidation. A study has shown that Lycium barbarum polysaccharide can regulate the phenotype and functional maturation of mouse bone marrow dendritic cells, which are important antigen-presenting cells in the body and play an important role in initiating the primary immune response.

4.Antitumor

Lycium barbarum polysaccharide can inhibit the growth of various tumors, and its mechanism of action is different. Some people think that Lycium barbarum polysaccharide can achieve the purpose of anti-tumor by activating the body's immune system, but there is still lack of reliable evidence for its inhibitory effect on tumors.

Lycium barbarum polysaccharide 3p significantly inhibits the growth of S180 sarcoma by increasing immunity and reducing lipid peroxidation. There are also data that the anti-tumor effect of Lycium barbarum polysaccharide is related to the regulation of calcium ion concentration. In the S phase of the division cycle, the proliferation of QGY7703 cells was inhibited and apoptosis was induced, the amount of intracellular RNA and the concentration of calcium ions increased, and the distribution of intracellular calcium ions was also changed.

Lycium barbarum polysaccharide can inhibit the growth of prostate cancer PC3 and DU145 cell lines, and there is a dose and time response relationship, causing DNA breakage in cancer cells, and inducing apoptosis through the expression of Bcl2 and Bax proteins. grow. Some studies have also found that the water extract of wolfberry can promote the apoptosis of liver cancer cells.

5.Regulate blood lipids and lower blood sugar

Wu et al. found that Lycium barbarum polysaccharide can reduce blood sugar and serum MDA and nitric oxide levels in non-insulin-dependent diabetes mellitus (NIDDM) rats, significantly increase serum SOD content, and reduce DNA damage in peripheral lymphocytes. Lycium barbarum polysaccharide can reduce the levels of blood glucose and blood lipids in alloxan-induced diabetic rabbits, and reduce the levels of blood lipids and blood glucose in high-fat diet-fed rats. Lycium barbarum polysaccharide at 2050mgkg-1 has the effect of protecting liver and kidney tissue in streptozotocin-induced diabetes, indicating that Lycium barbarum polysaccharide is a good hypoglycemic substance.

6.Anti-radiation

Lycium barbarum polysaccharide can promote the recovery of peripheral blood in mice with bone marrow suppression caused by X-ray and carboplatin chemotherapy, and can stimulate human peripheral blood mononuclear cells to produce recombinant granulocyte colony-stimulating factor (G-CSF). Lycium barbarum polysaccharide can reduce this damage, significantly improve the loss of mitochondrial sulfhydryl protein and the inactivation of SOD, catalase and GSHPx in liver cells caused by radiation, and its anti-radiation function is more obvious than tocopherol.

7.Neuroprotection

Yu et al. of the University of Hong Kong found that wolfberry extract can play a neuroprotective effect by resisting the stress level of the endoplasmic reticulum of nerve cells, and wolfberry polysaccharide has a protective effect on neurotoxicity caused by amyloid peptides. Amyloid peptide is one of the factors that promote neuron loss in the occurrence of Alzheimer's disease. Lycium barbarum polysaccharide can reduce the secretion of lactate dehydrogenase (LDH) and inhibit the activity of amyloid peptide protease. ) phosphorylation to prevent the apoptosis of nerve cells, reduce the phosphorylation of RNA-dependent protein kinase (PKR), and thus play a role in neuroprotection, which may play a role in the occurrence of Alzheimer's disease.

Human aging is mainly caused by cell oxidation. Lycium barbarum polysaccharide can directly scavenge hydroxyl radicals in vitro and inhibit the spontaneous or lipid peroxidation caused by hydroxyl radicals. Oral administration of Lycium barbarum polysaccharide can increase the activities of glutathione peroxidase (GSH-Px) and superoxide dismutase (SOD) in D-galactose-induced aging mice, thereby scavenging excess free radicals and delaying aging effect.

8.Anticancer effect

The biological effects of Lycium barbarum on cancer cells were observed by cell culture in vitro, which proved that Lycium barbarum had obvious inhibitory effect on human gastric adenocarcinoma KATO-I cells and human cervical cancer Hela cells. Lycium barbarum polysaccharide in the treatment of 20 cases of primary liver cancer showed that it can improve symptoms and immunocompromised conditions and prolong survival. Lycium barbarum polysaccharide has a regulatory effect on the antitumor activity of LAK cells in mice.

OEM services:

We can provide these OEM services for Wolfberry extract:

·Wolfberry juice powder

·Wolfberry extract capsules

·Wolfberry extract tablets

·Wolfberry extract powder with elegant small bag

·Other OEM services according to your requirements.

About more details, please don't hesitate to contact us.

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Shipping Delivery:

Express	Fedex	Ems	Epacket/NL post	DHL/USPS/TNT/UPS
Quantity	No weight limit	No weight limit	Under 2kg	No weight limit
Shipping time	7 to 10 days	10 to 15 days	About 30 days	7 to 15 days
Service	Door to door service; DDP service
Packing	Powder : Vacuum sealed foil packing OEM : Vacuum sealed foil packaging or packing for bottles

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